Thursday, December 29, 2016

Unusual syndromes deserve attention

The Alice in Wonderland Syndrome
https://www.ncbi.nlm.nih.gov/pubmed/25841113



LSD flashbacks
https://www.ncbi.nlm.nih.gov/pubmed/25841230

Expect these syndromes to become more prominent with appearance of new synthetic compounds, not only cannabinoids, but other molecules.

As for tools needed to study them, think of the charity luncheon foodborne disease outbreak challenge and think through the possibilities for latent variable analyses.

In the following version of the charity luncheon case study, the attack rates vary by the different ways to combine potential signs and potential symptoms into a syndromic case definition. This case study version eliminates that part, but imagine what you might try to do if you had attack rates specific to each food and to each combination of foods eaten and not eaten.

See Lesson 1.

2 comments:

  1. The Alice in Wonderland Syndrome: we may have seen a case of this at Sparrow Hospital. I tried to get the other residents interested in it, but they were all too skeptical. Had this diagnosis been my idea, I would have understood, but it was first suggested by the transferring attending....

    ReplyDelete
  2. Christopher Loren Thompson has left a new comment on your post "Unusual syndromes deserve attention":

    The Alice in Wonderland Syndrome: we may have seen a case of this at Sparrow Hospital. I tried to get the other residents interested in it, but they were all too skeptical. Had this diagnosis been my idea, I would have understood, but it was first suggested by the transferring attending....

    ReplyDelete

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