Possibly a goof about the new Canada cannabis laws

Interested in rummaging through old images and items ?

A place to rummage around for images and information you might be able to use.

Dropbox album

Orcutt on the topic of deviance and drug use

Link to cover image of article

Auditory Sensory Meridian Response: comments requested, anecdotes, use in prevention/treatment

Excerpt from Wikipedia entry:

Contemporary history

The contemporary history of ASMR began on 19 October 2007 when a 21-year-old registered user of a discussion forum for health-related subjects at a website called 'Steady Health',^[22] with the username 'okaywhatever', submitted a post in which they described having experienced a specific sensation since childhood, comparable to that stimulated by tracing fingers along the skin, yet often triggered by seemingly random and unrelated non-haptic events, such as 'watching a puppet show' or 'being read a story'.^[23]

Replies to this post, which indicated that a significant number of others experienced the sensation to which 'okaywhatever' referred, also in response to witnessing mundane events, precipitated the formation of a number of web-based locations intended to facilitate further discussion and analysis of the phenomenon for which there was plentiful anecdotal accounts,^[12][24]yet no consensus-agreed name nor any scientific data or explanation.^[17]

ASMR link

Link to photo image: https://peerj.com/articles/851/#fig-1

CC information: https://commons.m.wikimedia.org/wiki/File:ASMR_Map.png#mw-jump-to-license

The Devil’s Needle 1916 (Some holiday viewing pleasure ?)

“The Devil’s Needle stars silent goddess Norma Talmadge as a morphine-addicted artist’s model who sends a neurotic partner (Tully Marshall) down a path of moral deterioration.”

Link to CADL Kanopy (see MSU link below)

Link to MSU Kanopy

NYT interactive display on opioids

Link to show

ASAM Weekly in the News

Free subscription,

https://www.asam.org/resources/publications/asam-weekly

The weekly performs a consolidator function, akin to this blog but more focused.

These “in this issue” bullets are links to other news sources.

Not necessarily peer-reviewed material.

The assertions in these bullets are not those of the weekly’s editor.

These headlines might represent modern journalism in action, with a click bait function.

ASAM Definition of Addiction

(Notice the three key facets and the relative prominence and ordering, reflective of American but not all of western neuropsychiatry): (1) neuroadaptation, (2) disturbances of behavior (compulsion-like ‘inability to abstain consistently, dysfunction of behavioral control), and (3) disturbances of the mental life (obsession-like ‘craving’ and ‘dysfunctional emotional response’). Also disengaged from non-American western traditions of theoretical psychopathology (as a science), the interdependent facets of socially maladaptative behavior have been moved into the foreground. An alternative is multi-axial thinking within theories of (1) how things break down and go against life form viability and successful survival of the species and of the individual (survivorship of the individual, to the extent it can be usefully separated from reactions of other players in the individual’s social fields, as well as the social context) and the (2) the separable but interdependent responses of natural raters in social fields (e.g., interpersonal strife when the individual does not live up to expectations of the natural raters in these social fields). The theory that these facets are exchangeable manifestations of one another, with an underlying single latent dimensional structure, has influenced the measurement model such that diagnosis now requires little more than counting up what is thought to be exchangeable. Alternative theoretcal models specify value in maintaining a distinction between the ‘disease’ or ‘disorder’ as can be observed with social field/context held constant (which requires a separable measurement), versus manifestations that are interdependent but conceptually kept separate despite the interdependence and shared origins. 

To think about a clear example in medicine where we have another strong independendence but a compelling rationale to maintain separation, consider systolic versus diastolic blood pressure, where the inter-correlaion often shows up with correlation coefficients well above 0.65, and shared variance components due to common origins. Irrespective of the biometrical correlation and covariance structure, the conceptual theory of modern medicine leads us to specify a measurement model for hypertenion diagnosis that separates the systolic dimension of arterial stiffness (change in SBP with DBP dimension held constant) from the diastolic dimension of arterial compliace (change in DBP with SBP dimension held constant).

https://www.nature.com/articles/hr201095

https://www.ncbi.nlm.nih.gov/pubmed/18192832

https://www.ncbi.nlm.nih.gov/pubmed/22688268

Washington Post podcasts pertinent to NIH HEAL initiative

Podcast on Washington Live

Link to podcast page

Is left-censoring an issue? Left-truncation?

Han et al., November 2018

Stumbled across this CNN Gallery on Painkillers, Cocaine, and Heroin

Link to CNN Gallery through June 2016

Has it been updated since then?

Opioid deaths: How much is the increase due to change in surveillance approaches?

Counting opioid deaths

No need to minimize the suffering, but epidemiologists must ask the best questions possible while tooting their horns.

Kentucky Ayahuasca

link to article

“Real winners do not compete.”

https://www.weforum.org/agenda/2018/09/10-reasons-why-finlands-education-system-is-the-best-in-the-world

Juul personal story

NYTimes story about one teen’s rapid transition into nicotine dependence.

Precision in word choice reflects precision of one’s thoughts

Faithful readers know that I don’t appreciate the inter-penetration of political themes with our scientific work.

Hence, I avoid politically motivated terms as in ‘substance’ in lieu of ‘drug’ (or ‘marijuana’ in lieu of ‘cannabis’).

I also avoid stigma-laden American slang terms such as ‘addict’ and ‘addiction’ and I turn toward the WHO Expert Committees for an international perspective about ‘dependence’ syndromes.

I recently ran across a word choice essay on the topic of ‘fetal alcohol effect’ versus ‘fetal alcohol syndrome.’

You might enjoy reading the essay and the logic for avoidance of ‘fetal alcohol effect.’

‘FETAL ALCOHOL EFFECT’ — who needs the term?

Pot sobriety test: A little humor for the weekend

<2 minute video

Cannabis files

You might have thought liberalization of cannabis policies was something new.

Think otherwise.

Story about Michigan and 1972

Fake Molly in the news

Local Anti-Molly Initiatives

EVERY 25 SECONDS: THE HUMAN TOLL OF CRIMINALIZING DRUG USE IN THE UNITED STATES

Every 25 seconds... is link to the article summary and PDF.

The argument against repealing the current criminal approach rarely takes up serious consequences of this type.

Highly pertinent as jurisdictions debate whether to leave drug laws as they are, or to change them.

Question to ponder about our sons, daughter, or grandkids:

Which would you prefer to happen at age 18?

A. Development of cannabis use disorder (e.g., ‘hooked on pot’)?

B. Criminal record and perhaps incarceration time due to prosecution for possession?

(Learn the downstream social and economic consequences of A versus B. Which would you choose for your offspring?)

Perhaps my most political post yet!

Meth in the news in late October 2018

http://www.wamc.org/post/methamphetamine-roils-rural-towns-again-across-us

Transcript:

https://www.npr.org/sections/health-shots/2018/10/25/656192849/methamphetamine-roils-rural-towns-again-across-the-u-s

Citizen science and opioids

https://www.npr.org/sections/health-shots/2018/10/28/658476111/a-rural-community-decided-to-treat-its-opioid-problem-like-a-natural-disaster

Podcast: Finding Fixes webpage:

www.findingfixes.com

Pocketcast version:

https://pca.st/oWa4

BBC Share from Adnan Barazi

Thank you, Adnan!

https://www.bbc.com/news/av/world-us-canada-45968955/on-america-s-trail-of-destruction

Opioid tragedy

The Story

When Do We Get Around To Creating An International Cannabis Products Safety Commission?

Riff on an early meat packing industry cartoon:

NYT article on meat packing, unregulated.

Canada and Cannabis, October 2018

NYT article

Really? Truly?

JAMA articles on the ESI, race, ethnicity thread in this blog

Naomi Breslau: A Tribute

Link to the departmental tribute: http://www.epi.msu.edu/news/nbreslau/

A trace of her contributions in Ohio (Case Western Reserve) and Michigan (Henry Ford Health Systems, University of Michigan, and most recently, Michigan State University) via Web of Science:

Her Reach and Influence Across Fields:

Legal History of Psychoactive Drugs (Footnote on ‘Company Law’)

Article on the concept of a ‘company’ as is pertinent in the history of drug regulation.

There are some interesting historical details about British regulation of companies in this work.

If you see a corresponding American perspective, please add it as a comment.

Cannabis Safety? The Story From An Individual’s Perspective

An estimated 4 cases for every 100 newly incident users.

What makes online substance-use interventions engaging? A systematic review and narrative synthesis

What makes online substance-use interventions engaging? A systematic review and narrative synthesis

Cannabis images to spice up your lectures on stigma-laden and racist drug propaganda

Simply do a web browser search for: locoweed mexican carlotta

Illustrations of what you will find:

Selwyn D. Collins

Worked with Sydenstricker and Frost.

Studies of lifetime history of illness, using logistic curve learned from Raymond Pearl.

His publications

Paul Verlaine & Absinthe

Available online via MSU libraries.

visualizations from the Adol. Growth Atlas

This post is related to the visualization of feedback loop post (Thanks Alyssa!) 

*Cheating in a party environment increases before slightly decreasing at a higher IQ. Otherwise, the trend is downward as IQ increases. 

Google search- Suggestion is the psychological process by which one person guides the thoughts, feelings, or behavior of another person.

Why not place Antagonists & Overdose Aid instructions in 24/7 stores, fast food/coffee franchises, barber/hair salons?

“VA Adding Opioid Antidote To Defibrillator Cabinets For Quicker Overdose Response “

Some history on the logistic model

Link to history web page

Visualizations of note (Moderator will receive additions you submit via the comments panel.)

Original version, in color, is here on open access:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3012560/#!po=3.19149

Threats from Future Epidemics

Link to podcast of NIAID Director

Not epidemics of novel psychoactive drugs?

Can we treat our way out of this epidemic (without primary prevention and prevescalation)?

link to article

Link to article

Changing dynamics of the drug overdose epidemic in the United States from 1979 through 2016

1. Hawre Jalal1, 
2. Jeanine M. Buchanich2, 
3. Mark S. Roberts1, 
4. Lauren C. Balmert2,4, 
5. Kun Zhang5, 
6. Donald S. Burke3,*

 See all authors and affiliations

Science  21 Sep 2018:
Vol. 361, Issue 6408, eaau1184
DOI: 10.1126/science.aau1184

Modeling opioid policies

Useful examples of how survey estimates can go wrong.

West Virginia election Sept 2018

One of Bruce Dohrenwend’s Classic Articles

Deserves careful study.

BD’s Rema LaPouse Lecture

A quibble: This “three generation” model requires us to ignore the pioneering field surveys of early Norway, which pre-dated the work of Jarvis cited here as ‘first generation’ work. (They are dismissed as key informant surveys.) As well as the work of A.J. Rosenau (1916-17), which was not just a key informant survey. It had a two-stage design of the type we laid out for Mini-Mental and DIS studies of the 1980-85 era (following clues from Scott Henderson and Paul Duncan-Jones Australia study of life events), but Rosenau had no rigorous random sample of all participants.

e-health assessment tool collection

Please put URL link in the comments.

Still more on cannabis

XML text. See PDF link on original page.

Link to this article.

More on cannabis: A different qualitative research approach

Link to Bing queries approach

More on cannabis: A different qualitative research approach

Link to Bing queries approach

Qualitative research on cannabis

Link to full open access article.

Useful for several reasons, including the set and setting concepts that resonate with public health’s host and environment elements of the ‘epidemiological triad.’

The NIH project abstract:

Cannabis videos - not exactly a balanced curation

Videos link

Recovery article

New York Times September 1, 2018

Interesting surveillance approach described in this article

Hollerith, Billings, and the 1890 US Census

A note on Hollerith: https://en.wikipedia.org/wiki/Herman_Hollerith . Reading it, I learned another connectivity lesson. Hollerith worked for John Shaw Billings, whose name I recognized as someone connected to Hopkins who had worked out Vital Statistics for the US Censuses in the 19^th century. Apparently it was Billings who urged Hollerith to develop the punch card approach for the US Census of 1890. That census report is remarkable in that it apparently no longer exists (due to a fire and perhaps to some neglect). This is too bad because it included questions on disablement of household members and counted those affected by life-long cognitive problems (‘idiots’) and with other problems.

 

https://www.archives.gov/publications/prologue/1996/spring/1890-census-1.html

NYT Editorial: States Show the Way on the Opioid Epidemic

States Show the Way on the Opioid Epidemic

Who will do the state-level analysis that expresses this year’s opioid casualty attack rates as a function of state-level characteristics, including X-terms for what the NYTimes think is making a difference?

Ethnographic research in complement with survey and administrative records research

There is a podcast to listen to, but if you want to view the video of the session, it is here:

https://www.aei.org/events/using-ethnographic-research-to-understand-barriers-to-opportunity/

Features Robert Moffitt, Johns Hopkins professor, among other notables.

Podcast is here:

http://www.aei.org/multimedia/using-ethnographic-research-to-understand-barriers-to-opportunity/

Ethnographic storylet about a path to heroin problems can be heard, starting at about the 48 minute mark as shown on the image below:

Special treat day for Dr. Madhur Chandra

Cocaine Decisions

Lyrics

Performance

Enjoy!

Remember this day!

Extra treat I ran across: Unevaluated anti-drug PSAs that Frank Zappa performed for the Do It Now Foundation.

DIT Foundation also ran a mail service free anonymous drug testing lab.

Mail in specimen with code, anonymously.

They would post code and contents, dosages when possible.

Often showed contaminants.

Australian service of this type was described at CPDD2018

(Program and anstracts book at www.cpdd.org)

Many now are focused on NPS: ‘New Psychoactive Substances.’

[Why not ‘New Psychoactive Drugs’? In a word, politics (not science)].

Fingers crossed Madhur!

Heroin in Africa ?

Link to article

We have been discussing race and ethnicity question in the US Census (as well as citizen questions).

An interesting perspective: link

Lawsuits as a tool in dealing with drug crises

Link to transcript and podcast

Emergency Room Intervention Protocol

https://www.nytimes.com/2018/08/18/health/opioid-addiction-treatment.html

Old news on Exhibit about Neuroscientist Santiago Ramon y Cajal and his Drawings

https://nihrecord.nih.gov/newsletters/2014/12_05_2014/story1.htm

Martin I. Wilbert and Murray G. Motter, ‘Pioneer’ Drug Dependence Epidemiologists Responsible for Initial USPHS(NIH) Contributions to Our Field

Few scientists or practitioners in our field know about the United States Public Health Service “Laboratory of Hygiene” set up on Staten Island, New York, in 1887 with Dr. Joseph J. Kinyoun, Marine Hospital Service physician-bacteriologist, at the helm, and with a scientific staff restricted to medically trained physicians. The history of the US National Institutes of Health traces its roots back to this Hygienic Laboratory and indicates that the laboratory was moved to Washington, D.C., in 1891. In 1902 the laboratory received an appropriation that expanded its mission and allowed employment of non-physician scientists (https://history.nih.gov/exhibits/history/index.html)

Photo of JJ Kinyoun as a younger man, and Laboratory of Hygiene colleagues:

[Attribution-NonCommercial-ShareAlike 3.0 (CC BY-NC-SA 3.0 US)].

Photo of oil portrait of JJ Kinyoun as an older man:

CC BY-NC-SA 3.0 (US)

 

In the 1902 appropriation, the US Congress allowed the Hygienic Laboratory to expand and include new Divisions, including a Division of Pharmacology. The staffing restriction was removed to permit employment of non-MD scientists as professional staff members (https://history.nih.gov/exhibits/history/docs/page_02.html). Two of these scientists were Martin Inventius Wilbert, Phar.D., and Murray Galt Motter, who together became responsible for what appear to be the first US Public Health Service and possibly the first NIH contributions to the epidemiological study of the now-internationally regulated drugs (IRD) formerly mis-labeled as ‘narcotic drugs’ and including compounds as diverse as cocaine, cannabis, and opium.

< URL to link to the following article >

This is the earliest of Motter’s contributions I’ve been able to find:

< URL link to Motter, 1915 >

The earliest of Wilbert’s ‘firsts’ I’ve been able to find:

The elimination of the nostrum traffic, an evident duty of American physicians

 The record of Wilbert’s USPHS/(NIH) ‘firsts’ of this type also appears to be an initial early note in ‘occupational epidemiology’ or ‘occupational toxicology’ which concerning occupational intoxications:

Photo of MI Wilbert as a young adult. This photo accompanied his obituary in 1916, cited below:

Wilbert’s contributions were not limited strictly to pharmacology. They also covered legal issues, preventive medicine, and public health initiatives in the domain of prevention:

JSTOR link to this article from 1916.

D. Burkholder wrote a historical note about Wilbert, and published it in the American Journal of Hospital Pharmacy in 1968.

A Wilbert obituary was written in 1916 by George McCoy, who was then the Director of the laboratory.

< URL to link to the following article >

As is regrettably true for some contemporary epidemiologists and practitioners in our field, Wilbert sometimes used hyperbolic language and went ‘over the top’ in a fashion that tends to heap stigma upon affected individuals. Alas!

< URL link to the following article >